This paper compares the performance of methanol generator sets and diesel generator sets in plateau areas. Methanol generator sets have no power attenuation in high-altitude hypoxic environments, excellent low-temperature startability, smokeless and low emissions, lower fuel cost, high safety, and stable long-time operation. They effectively avoid downtime risks, reduce maintenance workload and operating costs, and are more adaptable to plateau drilling and winter field operations, making them an ideal power solution for wellsite applications.